Ten-year-old Isabella "Teaspoon" Marlene, raised by her mother Catty's old boyfriend Teddy Favors in Wisconsin, does some growing up when she agrees to take part in a mentorship program that pairs her with beauty queen Brenda Bloom, and her mother comes home from Hollywood.

Longtime friends Georgia, SuSu, Teeny, Diane, and Linda, known as the Red Hat Club, plot a special form of revenge when they learn that Diane's husband has used the couple's retirement money to buy a condo for his mistress.

Georgia, Linda, Diane, Teeny, and Pru, best friends since high school, need each other's support more than ever when Georgia's twenty eight year old daughter, Callie, becomes engaged to one of their former high school and college classmates, Wild Man Wade, a man whose youthful exploits are well-known to them all.

Childhood friends Lily and Val share everything--their feelings about love, success, identity, family, and even food--until an act of kindness rips their friendship apart and forces them to try to reconnect and recover their trust, while revealing a shocking secret that can change their relationship forever.

Noreen Kelly loses her job and her boyfriend on the same day, and as she wonders what to do with the rest of her life, she finds some surprising answers, some new friends, and a new passion while walking through her neighborhood.

Two years after giving up her high-paying Wall Street position to open a yoga studio, Charlie is reunited with three college friends, and as the women reconnect while taking classes at Charlie's studio, they inspire one another to take new chances and change their lives.

San Francisco detective Lindsay Boxer calls upon the members of the Women's Murder Club for help when a series of violent incidents put police on the trail of a killer or killers intent on murdering someone every three days. The investigation becomes urgent when Boxer learns that one of her friends is a target.

Birdie Cousins planned trip to Tuckernuck Island off the coast of Nantucket with her daughter Chess before her upcoming marriage takes a different turn when Chess suddenly breaks her engagement and her fiance dies in a rock-climbing accident.

Twenty-two-year-old Josh Flynn knows instinctively that his life is about to change when he sees three women, along with two young children, arrive at Nantucket airport, and as the summer progresses, he becomes the glue that holds things together as Vicki struggles with cancer, her sister Brenda deals with a career-ending scandal, and their friend Melanie comes to grips with a cheating husband and an unexpected pregnancy.

Polly, Beth, Carolyn, and Julia depend on friends, wine, and chocolate for support when forced to deal with a wealth of family problems, including Polly's new daughter-in-law, the ever-present ex-girlfriend of Beth's new beau, Carolyn's late-in-life pregnancy and her father's marriage to a younger woman, and the manipulative child of Julia's widowed boyfriend.